I was looking for the cause of a erratic jumping mouse cursor (about once every minute moving, clicking, …) when I suddenly realized that I had a GPS receiver still connected to a USB/serial adapter on the Windows machine. Cut that shit off, Microsoft! It’s 2010, no one is using serial mice anymore. And anyone who still does can sure be bothered to install the f*cking driver themselves!
Update: It’s a feature of the FTDIchip USB-to-serial driver and documented in the manual for the advanced driver options:
To disable auto detect, go to the device properties, advanced, and uncheck the “serial enumerator” feature.